But since I'm not nearly as musical as Steely Dan ...I plan to do it in my new kayak, assisted by my truck/camper.
I've posted this "plan" before, I know... But the difference is that now I actually have a watercraft and I've bought several guidebooks, so it's practically a done deal.
Since my kayak is inflatable, I could carry it in my little Hyundai Accent -- at 1/3 of the gas-cost of driving my truck/camper. But camping with the camper -- compared to in a little tent with my car -- is not only more comfortable...the extra comfort makes it much more likely that I'll linger in a great spot. And it makes sitting out bad weather easier -- or feasible at all.
Besides the states covered by the guides I've bought so far, I'll likely head up the eastern seaboard a ways -- maybe as far as Virginia.
For minimum humidity and bugs, spring or fall are my choices (and even winter in the warmest areas), but I already have a plan for this spring, so I plan to do this trip in the fall of this year.