Weight and GVWR
Weight is probably the biggest difference that you will find. For lightweight and quality of construction, there are really only two choices out there, FWC and ourselves.
Weight is the reason I went with a FWC. When fully loaded (full tank of gas, water, propane, food, me and the family) I am within a few hundred pounds of the GVWR of my full size Dodge 1/2 ton truck - I know because my company has a truck scale. I have been looking at 3/4 ton new and used trucks, but given the expense, have decided to stick with what I have unless a great deal comes along.
I also need 4x4 to reach some of my preferred sights and I would be afraid of what might happen to a lesser camper.